Thomas Tuchel faces a significant challenge in selecting the right-right back for England's upcoming match against DR Congo, with an injury crisis having ravaged the Arsenal squad.
Rice, who was rested against Panama due to his own injury, was surprisingly deployed at right-back in a crucial game against West Ham, a decision that was met with widespread criticism.
Former England defender Gary Neville was among those who questioned the call, labeling it a 'really poor decision' and stating that Rice is not suited to playing in defense.
Apart from Spence and Rice, Tuchel has also considered centre-backs Ezri Konsa and Trevoh Chalobah as potential replacements for James.
The England manager has only a few days to make a decision, with the Three Lions set to face DR Congo in Atlanta on Wednesday, July 1.